FAQ - rh isoimmunization
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How safe is the treatment for RH compatibility? What are the side effects seen on babies and mothers?

Consider the scenario of the mother having O- and the father A+, what are the chances that the rhogam based treatment will not cause any harm / side effects to the baby and the mother? What are the chances of the baby leading a normal life as against being retarded and having other problems? What does the dose of mercury (still contained in the rhogam drug???) do to the body of the mother? Are any other drugs available in the market that do not have these side effects? What is the best treatment available today for RH Compatibility?

If you plan on having anothor baby in the future it is the smart thing to do. Woman who don't get the rhogam and are rh negative and have a baby that is rh positive are putting all future pregnancies at risk. There is a chance that the second time around the mother's blood will attack the baby. Your doctor will discuss all the side effects with you. I have found a website that states in the 39 years rhogam has been used there has been no effect on the babies. Please look over this site for a better understanding and talk with your doctor.  (+ info)

Just found out i am rh sensitized but want a third baby. Anyone have a healthy baby after becoming sensitized?

I didnt receive the Rhogam shot during my first pregnancy because doctors said i was Rh+ but during my second pregnancy i was Rh- so i received the shot and when my son was born he had to have a blood transfusion. We was planning on trying for #3 and asked the doctor. She tested me and now i am Rh sensitized. Has anyone had a healthy baby after becoming sensitzed?? Any advice would be helpful! Thanks again!
about them saying i was RH+ during my first pregnancy, according to my New OBGYN they must have but the wrong blood type in my file! I know you cant be + then change to - that is just what is in my file from my old OBGYN

If you are Rh-, it won't show up or cause problems during your first pregnancy, because your body hasn't been "senstized" yet (this was the case for my mom and me) and you don't need Rhogam for the first. That doesn't mean you were RH+ and changed - you were still Rh-. However, after that first pregnancy you are sensitized after having an RH+ baby, and then you need Rhogam for all subsquent pregnancies if the babies are positive. Both of my younger brothers were born healthy with Rhogam, but it had to be monitored.  (+ info)

What can happen if an rh-negetive mother does not get her shot after delivery?

My daughter is rh-negetive and had her baby 1 week ago today. The baby was born at 41 weeks gestation. My daughter did get a shot for this at 28 weeks gestation but believes she did not get the shot at delivery.

the only reason you have to get your rhogam shot after delievery (within 48 hours) is if the baby has a positive blood type. My first daughter was B- so I didn't have to have the shot after delievery. My second daughter is O+ so I had to get the shot right after delievery. If you have a positive baby and don't get the shot after delivery there is a chance your body will produce the antibodies ( if any of the baby's blood mixed into the mother's bloodstream during delivery, which try to kill off a baby of a positive blood type in a Rh- mother because the antibodies see the baby as a parasite that needs to be rid of, kid of like a disease) and make your next pregnancy very difficult. So, as long as her baby doesn't have a positive blood type she'll be fine. But if the baby was a positive blood type and some of the baby's blood mixed into the mother's blood stream during delivery she'll probably have to get a rhogam shot before becoming pregnant the next time because her body will have already developed the antibodies seeing as she didn't recieve the shot soon enough.  (+ info)

How far along were you when you got your rh negative shot?

For those moms who have an rh negative blood type, how far along were you when you got your first rh negative shot? I am O- and my hubby is A+. I am 26 weeks now and wondering when I should be getting my shot.

I was 28 weeks; my hospital did it the same day that I did my glucose test...which is also done at 28 weeks. You will also get a shot at delivery.  (+ info)

What are the consequences of being Rh POSITIVE and receive Rhogam?

I am 23 weeks pregnant and my last blood test showed that I was O negative. However I have always believed that I was O positive. Is there any problem if I receive the Rhogam shot even if I am not Rh negative?
All the information I have found is related to Rhogam been given to Rh negative mothers.
Thanks for your help!

Get another blood test, I don't believe it's dangerous but if it's unneeded don't get it. Also, in a normal birth (no pitocin, expectantly managed third stage - no cord yanking) Rh- moms don't need it either.  (+ info)

What is the way out to get the list of Rh negative B blood group persons?

Rh negative B blood group appears to be very rare. Then how to get it in case of emergency?

This is the job of the bloodbank and such a listing is strictly confidential. Even if you were to have a listing, blood must be processed after it's collected as it is rarely used as whole blood, so the list itself would be of limited value. (Blood is fractionalized and broken down into Packed cells, cryoprecipitate, etc. so that patients receive what they need, not an entire unit)
First of all, when a patient who is bleeding profusely comes through the ER, they are given a couple of units of O Negative, a universal donor while they are typed and crossmatched. They either have this blood type or a courier obtains it from a neighboring blood bank. I have even seen it delivered via helicopter. We also have non-blood plasma expanders which can also be used until the patients blood type can be located. There are many different rare types of blood. Unless you are travelling to a country with a Third World Medical system, this is rarely a significant issue in the recovery of most patients. Best wishes.  (+ info)

Explain why an Rh-negative person does not have a transfusion reaction on the first exposure?

Explain why an Rh-negative person does not have a transfusion reaction on the first exposure to Rh-positive blood but does have a reaction on the second exposure. What happens when an ABO blood type is mismatched for the first time?

the body has to build antibodies. On first reaction the body has no antibodies, however on second reaction the body has had time to build antibodies to that rh negative.  (+ info)

Why is there a problem when Rh negative mother gives birth to Rh positive fetus?

I know why. But what I don't understand is why the same problem doesn't exist when an Rh positive mother gives birth to Rh negative fetus???

What is Rh sensitization during pregnancy?
If you are Rh-negative, your red blood cells do not have a marker called Rh factor on them. Rh-positive blood does have this marker. If your blood mixes with Rh-positive blood, your immune system will react to the Rh factor by making antibodies to destroy it. This immune system response is called Rh sensitization.

What causes Rh sensitization during pregnancy?
Rh sensitization can occur during pregnancy if you are Rh-negative and pregnant with a baby ( fetus) who has Rh-positive blood. In most cases, your blood will not mix with your baby’s blood until delivery. It takes a while to make antibodies that can affect the baby, so during your first pregnancy, the baby probably would not be affected.

But if you get pregnant again with an Rh-positive baby, the antibodies already in your blood could attack the baby’s red blood cells. This can cause the baby to have anemia, jaundice, or more serious problems. This is called Rh disease. The problems will tend to get worse with each Rh-positive pregnancy you have.

During your first pregnancy, your baby could be at risk for Rh disease if you were sensitized before or during pregnancy. This can happen if:

You had a previous miscarriage, abortion, or ectopic pregnancy and you did not receive Rh immune globulin to prevent sensitization.
You had a serious injury to your belly during pregnancy.
You had a medical test such as an amniocentesis or chorionic villus sampling while you were pregnant, and you did not receive Rh immune globulin. These tests could let your blood and your baby’s blood mix.
Rh sensitization is one reason it’s important to see your doctor in the first trimester of pregnancy. It doesn't cause any warning symptoms, and a blood test is the only way to know you have it or are at risk for it.

If you are at risk, Rh sensitization can almost always be prevented.
If you are already sensitized, treatment can help protect your baby.
Who gets Rh sensitization during pregnancy?
Rh sensitization during pregnancy can only happen if a woman has Rh-negative blood and only if her baby has Rh-positive blood.

If the mother is Rh-negative and the father is Rh-positive, there is a good chance the baby will have Rh-positive blood. Rh sensitization can occur.
If both parents have Rh-negative blood, the baby will have Rh-negative blood. Since the mother’s blood and the baby’s blood match, sensitization will not occur.
If you have Rh-negative blood, your doctor will probably treat you as though the baby’s blood is Rh-positive no matter what the father’s blood type is, just to be on the safe side.  (+ info)

My blood type is rh negative. Am i going to have problems with miscarriages?

I have a 2 year old son and had no problems during pregnancy or labor. But I just miscarried 2 weeks ago and am worried that this might happen again since I am rh negative. I cannot go through loosing another baby! I've heard that the first baby comes easily, but future pregnancies are more problematic. Do miscarriages happen more often for those of us with this cursed blood type?

I too am rh negative I have had 3 pregnancies with 3 beautiful girls.They all had rh positive blood and I had to get the rhogam shot shot at 7 months and right after delivery because when your child is rh positive and you don't get the shot following delivery it can affect your next pregnancy .Somehow your body makes antibodies to fight against your unborn baby if you don't get the shot.I am very sorry for your loss.God bless and good luck.  (+ info)

My doctor wants to test me with RH compatibility, do I need the cooperation of my baby's father?

I am not in contact with my unborn child's father anymore. However, the RH compatibility test might be necessary for me to?

Please advise.
I'm asking if I'd need to call him to ask if he's got a negative or a positive blood type.

it'sa simple blood test, nothing to do with the father whatsoever

People with different blood types have proteins specific to that blood type on the surfaces of their red blood cells. There are four blood types - A, B, AB, and O.

Each of the four blood types is additionally classified according to the presence of another protein on the surface of red blood cells that indicates the Rh factor. If you carry this protein, you are Rh positive. If you don't carry the protein, you are Rh negative.

Most people - about 85% - are Rh positive. But if a woman who is Rh negative and a man who is Rh positive conceive a baby, there is the potential for a baby to have a health problem. The baby growing inside the Rh-negative mother may have Rh-positive blood, inherited from the father. Approximately half of the children born to an Rh-negative mother and Rh-positive father will be Rh positive.

Rh incompatibility usually isn't a problem if it's the mother's first pregnancy because, unless there's some sort of abnormality, the fetus's blood does not normally enter the mother's circulatory system during the course of the pregnancy.

However, during delivery, the mother's and baby's blood can intermingle. If this happens, the mother's body recognizes the Rh protein as a foreign substance and can begin producing antibodies (protein molecules in the immune system that recognize, and later work to destroy, foreign substances) against the Rh proteins introduced into her blood.

Other ways Rh-negative pregnant women can be exposed to the Rh protein that might cause antibody production include blood transfusions with Rh-positive blood, miscarriage, and ectopic pregnancy.

Rh antibodies are harmless until the mother's second or later pregnancies. If she is ever carrying another Rh-positive child, her Rh antibodies will recognize the Rh proteins on the surface of the baby's blood cells as foreign, and pass into the baby's bloodstream and attack those cells. This can lead to swelling and rupture of the baby's red blood cells. A baby's blood count can get dangerously low when this condition, known as hemolytic or Rh disease of the newborn, occurs.  (+ info)

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