FAQ - splenic infarction
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splenic infarction?


my son son has the sickle cell trait. I am doing research on this and have read that it could cause splenic infarction. I do not understand what this is. Does anyone know?
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Splenic infarction is blockage of the spleen by the damaged blood cells. The sickle cells, which are still produced with sickle cell trait, are sequestered and degraded by the spleen. Unfortunately around half of the red blood cells in your son's body prodcued are sickle cells so the spleen is being over worked trying to take all of these cells out of the bloodstream, which will possibly cause and infarction. Infarction is the fancy medical term for blockage of a vessel. You have probably heard of a heart attack, which is just a myocardial infartion(a blockage of a heart vessel). So splenic infarction would be a blockage of a splenic vessel, the problem is that it can cause necrosis(tissue death) in the spleen, lead to splenomegaly(enlarging of the spleen) and may have to be treated by removing the spleen. I hope this helps a little.  (+ info)

What are the splenic complications of sickle cell anaemia?


I do know some but I am not sure if they are anymore.
-Hyposplenism
-Acute Splenic sequestration crises
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repeated spleenic infarctions and resulting in auto spleenectomy within first few years of life,the infarctions kill the spleen  (+ info)

What is the difference between infarction and gangrene?


The morphology of both is the same,that is,ischemic necrosis.I know gangrene involves putrefaction which infarction does not.Then,why is repair by fibrosis possible only in infarction,but not in gangrene?What are the exact definitions of infarction and gangrene?Please differentiate them clearly.
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Infarction- (1) engorgement or stoppage of a vessel. (2) development or presence of an infarct (a localized area of ischemic necrosis produced by occlusion of the arterial supply or venous drainage of the part.)
Cardiac infarction- myocardial infarction.
cerebral infarction- an ischemic condition of the brain, causing a persistent focal neurological deficit in the area affected.
intestinal infarction- occlusion of an artery or arteriole in the wall of the intestine, resulting in the formation of an area of coagulation necrosis.
myocardial infarction- formation of an infarct in the heart muscle, due to interruption of the blood supply to the area.
pulmonary infarction- infiltration of an airless area of lung with blood cells, due to obstruction of the pulmonary artery by an embolus or thrombus.

gangrene- death of the tissue in considerable mass, usually associated with loss of vascular (nutritive) supply and followed by bacterial invasion and putrefaction.  (+ info)

What is the greatest danger of a splenic rupture?


What is the greatest danger of a splenic rupture?
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  (+ info)

What medical term for cerebral infarction can trigger Google health search?


My friend's father suffers from cerebral infarction and I wanna look up some helpful information for him. I know Google health search can be triggered by medical glossary, but not cerebral infarction. What medical term for the disease cerebral infarction can i use to trigger Google health search?
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Stroke, cerebral vascular accident, aneurysm (different from prior two) TIA (transischemal attack)  (+ info)

How fast does nitroglycerin act when used to treat a myocardial infarction, i.e. when given in tablet form?


I have been trying to find information online about the speed and efficacy of nitroglycerin in tablet form when used to treat a myocardial infarction. It's for a short story I am writing, and I can't finish until I find this information. I don't want to just make something up.
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Nitroglycerin doens't actually do anything to treat a myocardial infarction. It is best for angina- the squeezing pain people get in their chest when the blood vessels around their heart are constricted but not completely closed. For angina, it works in seconds to relieve the pain and relax those blood vessels so the heart gets more blood.
During a heart attack, the coronary vessels close completely, and blood flow to part of the heart is cut off. A person who takes nitroglycerin for angina should worry that they are having a heart attack if they take nitroglycerine and the pain does not go away. They should take an aspirin immediately and go to the ER to be given other meds or have a stent put in to open the artery back up.  (+ info)

Can pericardial effusion lead to myocardial infarction or any other serious consequence?


I am seeking to find out if pericardial effusion resulting from a viral infection can lead to myocardial infarction and/or any other serious consequence?
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if left untreated it can lead to cardiac tamponade, which is compression of the heart due to a large increase of fluid in the pericardium. this condition is life-threatening as it prevents the heart from pumping effectively.  (+ info)

What is the main cuase of ischemia and how is it linked to myocardial infarction, along with thrombosis.?


Also with atheroma.

Im cofnused with the following terms and how they relate to cuasing myocardial infarction:
1)ischemia
2)thrombosis
3)atheroma
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The buildup of atheroma or fatty plaque in the wall of the coronary artery narrows the lumen of the artery resulting in ischemia or inadequate blood flow to the heart. The atheroma may ulcerate releasing materials that cause blood to clot on the surface of the plaque. As the clot enlarges it totally obstructs the artery causing a myocardial infarction or death of cardiac tissue downstream to the obstruction.  (+ info)

what is the difference between a heart failure from myocardial infarction?


can you have a heart failure without a myocardial infarction? or can you have a myocardial infarction without a heart failure? i'm really confused..
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heart failure happens when the heart fails to pump adequate amounts of blood around the body... there are many reasons for this.
myocardial infarction happens when an artery that feeds the heart muscle becomes obstructed, fails to deliver blood to the heart muscle itself and the muscle dies where it is lacking circulation.  (+ info)

Medical/Author Question: How to induce an infarction in a limb?


I am a writer currently on work on a short story where the main character is a mentally disturbed medical student. After watching an episode of "House", he gets the crazy idea to induce an infarction in his own leg because he wants the sympathy and attention. Is there any way to do this or is it only a natural occurrence? Any other ideas on how to cripple his leg? I can include a thank you in my acknowledgments to whomever is able to help me. Thanks a bunch.
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An infarction in a limb is basically a heart attack except the blood clot is somewhere else. There are things that the character could do to make him more likely to get an infarction, but there's no real way to make it happen.
It sounds like your character has Munchausen Syndrome. This is a condition where the patient induces injury to get the attention of doctors. Some tricks that munchausen syndrome patients use are injecting themselves with bacteria, milk, feces, gasoline, battery acid, etc. Sometimes they will also take medications to mimic a medical problem. I don't know how important to the story it is that they injur their leg, but they could just make themselves sick in another way.

Hope this helps.  (+ info)

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