How do the kidney and vascular diseases contribute to hypertension?
Primarily, it's the other way around. Hypertension contributes to kidney and vascular diseases!
The kidneys autoregulate blood flow by controlling the diameter of tiny blood vessels going into and out of each of the microscopic urine-making structures called the "nephrons". When the pressure is high, these blood vessels become stiff from overgrowth of the muscle walls used to resist the flow. The nephrons themselves are damaged from pressure, and the organ's microstructure is slowly replaced by scar.
High blood pressure also represents a challenge to the rest of the bodily blood vessels, which become thickened in response to the pressure, and which are prone to shearing injuries to the lining. This is especially true when the lining is infiltrated with cholesterol in the form of atherosclerotic plaques. As the blood vessels become thickened and stiff, the pulsations of flow hammer away at the walls, creating things like aneurysms (balloon-like dilations prone to rupture) and blockages where the atherosclerotic plaques rupture and clot. This latter mechanism is commonly the cause of heart attack and stroke, as well as other end-organ damage.
There is one particular phenomenon, however, that DOES relate to your exact question. There is a condition known as renovascular hypertension, and this is one of the forms of high blood pressure that can be traced back to a treatable cause, and can be "cured" by an intervention. Most often, of course, hypertension is considered to be "essential hypertension" which means that there is no specific cause identified, and the hypertension itself needs to be treated because of the risks it poses to the patient's health.
Renovascular hypertension is a problem that occurs in those people who develop flow limiting atherosclerotic plaques in the arteries leading off to the kidneys. When this happens, the flow to the kidneys is substantially decreased, and the kidneys are "fooled" into thinking that there is a problem of flow throughout the body. The kidneys react to a situation that, if the arteries to the kidneys were normal, would probably represent low circulating blood volume. Basically, the kidneys are unable to tell the difference between low flow because the arteries are bad, and low flow because the patient lost a lot of blood from an injury.
The response from the kidney suffering low flow comes in the form of a hormone. This hormone is called "renin" and it has one job. Renin circulates in the blood and it turns a protein called "angiotensinogen" into "angiotensin 1". Angiotensin 1 is a hormone that increases the tension in blood vessels, but more importantly, it is a precursor to "angiontensin 2", which is what it its turned into immediately after passing through the lungs. Angiotensin 2 is one of the most powerful vaso-constricting hormones we have. It increases the blood pressure dramatically.
Renovascular hypertension can be treated by procedures which open up the narrowed blood vessel, but the key is that the problem needs to be recognized first! Sometimes people with this problem go unrecognized for long periods of time.
I hope that helps! (+ info
I want a brief note on CARDIO VASCULAR diseases and its prevention?
please give me a link of suitable website for this.
u may search it on wikipedia. any way I've given its link in source (+ info
What percentage of senior citizens 65 yrs or older die of CVD - cardio vascular diseases?
If possible could you list the source that you found your information in?
Common sense will indicate to you that it is 100%. When you die, you can bank you bottom dollar on it, that the cause of death listed on the death certificate will be cardiac arrest. It is a catch all diagnosis for death certificates, because once your hearts quits ticking, you're dead. (+ info
What type of Doctor specializes in Peripheral Vascular Diseases?
like Deep Vein Thrombosis (sp?)
Cardiovascular surgeons-surgery of peripheral blood vessels, i.e. those outside of the chest (usually operated on by cardiovascular surgeons) and of the central nervous system (treated by neurosurgery).
Deep venous thrombosis (DVT) is clotting of blood in a deep vein of an extremity (usually calf or thigh) or the pelvis. DVT is the primary cause of pulmonary embolism. DVT results from conditions that impair venous return, lead to endothelial injury or dysfunction, or cause hypercoagulability. DVT may be asymptomatic or cause pain and swelling in an extremity. Diagnosis is by history, physical examination, and duplex ultrasonography, with D-dimer or other testing as necessary. Treatment is with anticoagulants. Prognosis is generally good with prompt, adequate treatment; common long-term complications include venous insufficiency with or without postphlebitic syndrome. (+ info
name four diseases/ injurise of the Cardio Vascular Sytem?
thanks... all i need are 4 and maybe just a basic description of what they are... THANKS
even if you only know one that helps....
What are the main differences between Vascular Dementia and Alzheimer's Disease?
A member of my family has been diagnosed with Vascular Dementia so the more detail someone can give me, the better. Many thanks.
Vascular dementia is caused by narrowing arteries cutting off oxygen supply to the brain cells - proper medication can really help/even improve mental function IF brain cells haven't been impaired by a stroke. No one yet knows what causes Alzheimer's, but there are connections to the brain not being able to rid itself of waste materials the same way "normal" brains do and that's what many of the meds work on. An Alzheimer's diagnosis is more discouraging because the medications are still all pretty new/experimental and only slow down the progress of the disease, at best. Chances are, with Vascular Dementia, if your family member is able to exercise a little, gets really good nutrition and treatments that clear out arteries, there's a chance for a better quality of life than with Alzheimer's. Good for you for caring enough to search out answers! (+ info
Peripheral Vascular Diseases!?
On Oct. 4, 2006 I underwent CABG x5 bypasses. My concern is that I may have widespread atherosclerosis. For 5-8 years I have had some symptoms of PAD in my lower extremities. Including Intermitant Claudication and ED. I wonder if it may be affecting my vital organs as well. I also am concerned about Carotid Artery Disease. Are these concerns real or unnecessary? I plan to see my PCP but wanted an openion from someone in the health sciences especially with regard to vascular science. Am I too concerned? Not enough?
I also have COPD (Emphysema), Idiopathic Pulmonary Fibrosis, Sleep Apnea, Hypertension and Bipolar Disorder.
I currently take 325mg Aspirin, 500mg Nician, 10/80mg Vytorin and 160mg Triglide to help with the cholesterol. I also take 50mg Toprol-XL for the hypertension.
You may very well have widespread blockage, but it apparently isn't severe, or your doctors would have brought it to your attention, prior to the bypass. My mom recently was showing signs of poor circulation, her little toe was turning black and was very painful. She had the angioplasty with a stent. Her blockage was in the groin area, where the arteries split into the legs. Your blockage was in the aorta, coming from the heart down across the abdomen. With your other health problems, you certainly suffer with poor circulation, and lack of oxygen in the blood. You should be concerned with your health, but my feeling is this, you made it throught a serious bypass surgery, so your health is actually pretty good overall. Vascular surgeons are very well educated, I feel your doctor is your best advice giver. Be sure to bring your concerns to the table when you see the doc. Make a list if necessary, but make sure you understand what is being said, ask more questions if you don't. If you smoke, you must stop. My mom refuses to, and her health is deteriorating because of this. She simply doesn't believe that cigarettes can cause her severe health problems, she always blames something else. Good luck to you, keep your appt. (+ info
Cardio Vascular Diseases?
What are the FOUR cardiovascular diseases??
There are many different types of cardiovascular diseases, not just four. If this is a homework question... you should find out on your own. (+ info
Vascular disease involve only the heart and the brain?
IS it true that vascular disease involve only the heart and the brain? If not, please explain why. Thanks!
Vascular disease harms blood flow in arteries and veins throughout your body. It causes everything from leg pain to poor kidney function and stroke. Problems of the vascular system are common and can be very serious.
For example:- Varicose veins are a vascular disease. (+ info
Is there any effectilve medicine to treat peripheral vascular disease ?
Mr. Banzai has done a good job in answering the question regardig "heparin". Please tell me whether there is medicine to cure/treat peripheral vascular disease. What diseases belong to peripheral disease. Thanks.
webmd.com or nih.gov or mayoclinic.com (+ info
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