A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of procollagen and may act as a regulator of extracellular matrix deposition. alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several protein isoforms.

Symptoms and diagnosis




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