Genetic diseases that are linked to gene mutations on the x chromosome in humans (x chromosome, HUMAN) or the x chromosome in other species. Included here are animal models of human X-linked diseases.
Focal dermal hypoplasia
Emery–Dreifuss muscular dystrophy
![LNS is inherited in an X-linked recessive fashion. LNS is due to mutations in the 'HPRT1' gene,[http://ghr.nlm.nih.gov/condition=leschnyhansyndrome Lesch-Nyhan syndrome.] Genetics Home Reference. Retrieved on 2007-05-24.[http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.section.298 Lesch-Nyhan syndrome.] NCBI Genes and disease. Retrieved on 2007-04-12 so named because it codes for the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT or HGPRT, ). This enzyme is involved in the biochemical pathways the body uses to produce purines, one of the components of DNA and RNA. Defects of this enzyme lead to increased production of uric acid. Since the 'HPRT' gene is located on the X chromosome, LNS is an X-linked inherited disease.](https://lookformedical.com/img/c/c7/X-linked_recessive.svg)