Keratoderma, Palmoplantar (Hyperkeratosis Palmaris et Plantaris; Keratosis Palmaris et Plantaris; Keratosis, Palmoplantar; Meleda Disease; Palmoplantar Keratoderma)
Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).