Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial gigantism of the hands and/or feet, asymmetry of the limbs, plantar hyperplasia, hemangiomas (hemangioma), lipomas (lipoma), lymphangiomas (lymphangioma), epidermal NEVI; macrocephaly; cranial hyperostosis, and long-bone overgrowth. Joseph Merrick, the so-called "elephant man", apparently suffered from proteus syndrome and not NEUROFIBROMATOSIS, a disorder with similar characteristics.

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