Translocation, Genetic (Chromosomal Translocation; Translocation, Chromosomal)

A type of chromosome aberration characterized by chromosome breakage and transfer of the broken-off portion to another location, often to a different chromosome.


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Robertsonian translocation

Coat of arms of Massachusetts, adopted in 1775 (by Legislature, re-affirmed by Governor Hancock and Cabinet on December 13, 1780)

ARIAD Pharmaceuticals

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ARIAD Pharmaceuticals

This WikiProject is about the U.S. state of Massachusetts.

ARIAD Pharmaceuticals

Variations on a common tablet design, which can be distinguished by both color and shape

ARIAD Pharmaceuticals

Crystal structure of the second generation Bcr-Abl tyrosine-kinase inhibitor nilotinib (red) in complex with an Abl kinase domain (blue). Nilotinib is used to treat chronic myelogenous leukemia (CML), a hematological malignancy.

Philadelphia chromosome

A metaphase cell positive for the 'bcr/abl' rearrangement (associated with chronic myelogenous leukemia) using FISH. The chromosomes can be seen in blue. The chromosome that is labeled with green 'and' red spots (upper left) is the one where the rearrangement is present.

Philadelphia chromosome

Schematic of the Philadelphia chromosome formation

Philadelphia chromosome

Diagnosis and therapies

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Symptoms and diagnosis

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Wikipedia

Philadelphia chromosome - WikipediaFusion gene - WikipediaHOXA9 - Wikipedia

More information

Reported cases - Summary of cases reported on this diseaseWHO - World Health OrganizationPubMed - A service of the National Library of Medicine and National Institutes of HealthMEDLINE - Literature from the National Library of MedicineMeSH - Medical Subject HeadingsDeCS - Health Sciences Descriptors

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