A 9-kDa protein component of VERY-LOW-DENSITY lipoproteins. It contains a cofactor for lipoprotein lipase and activates several triacylglycerol lipases. The association of Apo C-II with plasma chylomicrons; VLDL, and HIGH-DENSITY lipoproteins is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (hyperlipoproteinemia type i) and is therefore called hyperlipoproteinemia type IB.

Symptoms and diagnosis



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