The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields complement c5a and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.

Symptoms and diagnosis



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