A Janus kinase subtype that is involved in signaling from growth hormone RECEPTORS; prolactin RECEPTORS; and a variety of CYTOKINE RECEPTORS such as erythropoietin RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of myeloproliferative disorders.

Symptoms and diagnosis



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