MPTP Poisoning; MPTP Neurotoxicity Syndrome

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Symptoms:

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	Active principles	Rating	Bibliogr.
1	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	100	+
2	Tyrosine 3-Monooxygenase	37	+
3	3,4-Dihydroxyphenylacetic Acid	34	+
4	Indazoles	33	+
5	Dopamine	33	+
6	Glial Fibrillary Acidic Protein	28	+
7	1-Methyl-4-phenylpyridinium	15	+
8	Mitochondrial Membrane Transport Proteins	9	+
9	alpha-Synuclein	6	+
10	Homovanillic Acid	6	+
11	Dopamine Plasma Membrane Transport Proteins	5	+
12	Pargyline	5	+
13	Nerve Tissue Proteins	4	+
14	Pyridinium Compounds	4	+
15	Acrylamide	4	+
16	Amyloid beta-Peptides	4	+
17	Antivenins	3	+
18	N-Methyl-3,4-methylenedioxyamphetamine	3	+
19	Quinolinic Acid	3	+
20	Tritolyl Phosphates	3	+
21	Methamphetamine	3	+
22	Semicarbazones	3	+
23	Kainic Acid	3	+
24	Glutamic Acid	3	+
25	Synucleins	3	+
26	Levodopa	3	+
27	Monoamine Oxidase	3	+
28	Pyridines	3	+
29	Biogenic Monoamines	2	+
30	Oxidopamine	2	+
31	Viologens	2	+
32	S100 Proteins	2	+
33	Parvalbumins	2	+
34	Nuclear Receptor Subfamily 4, Group A, Member 2	2	+
35	Selegiline	2	+
36	Receptors, N-Methyl-D-Aspartate	2	+
37	Mercury Compounds	2	+
38	Nitric Oxide Synthase Type I	2	+
39	Cyclophilins	2	+
40	Rotenone	2	+
41	Glutathione	2	+
42	G(M1) Ganglioside	2	+
43	Reactive Oxygen Species	2	+
44	Snake Venoms	2	+
45	Hydroxyl Radical	2	+
46	N-Methylaspartate	2	+
47	Integrin alpha2beta1	2	+
48	Nitro Compounds	2	+
49	NF-E2-Related Factor 2	2	+
50	Hexanones	2	+
51	Amino Acids, Diamino	2	+
52	Plant Extracts	2	+
53	S100 Calcium Binding Protein beta Subunit	2	+
54	Voltage-Dependent Anion Channels	2	+
55	bcl-2-Associated X Protein	2	+
56	Thiazoles	2	+
57	Atractyloside	2	+
58	Memantine	2	+
59	Electron Transport Chain Complex Proteins	2	+
60	Nerve Growth Factors	2	+
61	Methylmercury Compounds	2	+
62	Tetrazolium Salts	2	+
63	Manganese	1	+
64	Glycogen Synthase Kinase 3	1	+
65	Prions	1	+
66	Nestin	1	+
67	Acetylcholinesterase	1	+
68	Isoxazoles	1	+
69	Dizocilpine Maleate	1	+
70	Dieldrin	1	+
71	Clioquinol	1	+
72	Intermediate Filament Proteins	1	+
73	Peptide Fragments	1	+
74	RNA, Messenger	1	+
75	Serotonin	1	+
76	Benzothiazoles	1	+
77	Plicamycin	1	+
78	Vesicular Monoamine Transport Proteins	1	+
79	Ubiquitin	1	+
80	Superoxide Dismutase	1	+
81	Misonidazole	1	+
82	Hexanes	1	+
83	Organoplatinum Compounds	1	+
84	tau Proteins	1	+
85	Proto-Oncogene Proteins c-bcl-2	1	+
86	Protein Phosphatase 2	1	+
87	Nitric Oxide	1	+
88	Triterpenes	1	+
89	Receptors, Dopamine D2	1	+
90	Otx Transcription Factors	1	+
91	Pentylenetetrazole	1	+
92	Crotalid Venoms	1	+
93	Nomifensine	1	+
94	Vesicular Biogenic Amine Transport Proteins	1	+
95	Biogenic Amines	1	+
96	Spiperone	1	+
97	Mazindol	1	+
98	Nitric Oxide Synthase Type II	1	+
99	Normetanephrine	1	+
100	Benzoxazoles	1	+
101	Drugs, Chinese Herbal	1	+
102	Hydrogen Peroxide	1	+
103	Choline O-Acetyltransferase	1	+
104	Paclitaxel	1	+
105	Carboplatin	1	+
106	Nitric Oxide Synthase	1	+
107	Receptors, Nicotinic	1	+
108	Receptors, Dopamine	1	+
109	Protein Disulfide-Isomerases	1	+
110	Propionates	1	+
111	Electron Transport Complex I	1	+
112	Oligonucleotide Probes	1	+
113	Caspase 3	1	+
114	Steroids	1	+
115	Altretamine	1	+
116	Presenilin-1	1	+
117	Nuclear Proteins	1	+
118	Calcium	1	+
119	Antigens, CD147	1	+
120	Vinblastine	1	+
121	Ubiquitin-Protein Ligases	1	+
122	Amino Acid Transport System X-AG	1	+
123	Receptors, Dopamine D3	1	+
124	Ifosfamide	1	+
125	Glutathione Peroxidase	1	+
126	Cysteine	1	+
127	Glucocorticoids	1	+
128	Minocycline	1	+
129	Nicotine	1	+
130	Amyloid beta-Protein Precursor	1	+
131	Cisplatin	1	+
132	Piperidines	1	+
133	Immunoglobulins, Intravenous	1	+
134	Curcumin	1	+
135	Riluzole	1	+
136	gamma-Aminobutyric Acid	1	+
137	Chlorides	1	+
138	Homeodomain Proteins	1	+
139	Cyclosporine	1	+
140	Vincristine	1	+
141	Benserazide	1	+

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