Cases reported "Adenocarcinoma"

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11/820. Percutaneous transrenal ureteroneocystostomy.

    Advanced cancer of the prostate causes mechanical obstruction of the ureteral orifice in 10% of patients. In our patient with advanced prostate carcinoma, after the usual method of placement of a ureteral stent had failed, antegrade percutaneous ureteroneocystostomy with placement of a double-J performed by means of the Lawson retrograde nephrostomy set. After removal of the stent 8 months later, the anastomosis functioned without a decrease in caliber until the patient died 2 years later. Our technique represents another new option for the treatment of such patients.
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12/820. disseminated intravascular coagulation.

    OBJECTIVES: To provide an overview of the pathophysiology, manifestations, diagnosis, and treatment of disseminated intravascular coagulation (DIC) as it occurs in cancer. DATA SOURCES: Published articles, research reports, and book chapters. CONCLUSIONS: The syndrome of DIC is a serious hypercoagulation state that in its acute form may be life-threatening. The hemorrhage and intravascular coagulation that occur with DIC may lead to irreversible morbidity and mortality. Prompt recognition and emergency treatment are necessary to help minimize morbidity and mortality. IMPLICATIONS FOR NURSING PRACTICE: nurses can play an important role in early recognition of DIC to allow for prompt intervention. nurses caring for patients affected by DIC will be providing complex nursing care, in addition to psychosocial support to patients and families.
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13/820. Paraneoplastic limbic encephalitis associated with small cell carcinoma of the prostate.

    A 76-year-old man with primary small cell carcinoma of the prostate died after a subacute illness marked by memory loss and truncal ataxia Post-mortem examination of the central nervous system was consistent with limbic encephalitis and cerebellar degeneration. Although limbic encephalitis is a known complication of small cell carcinoma of the lung, this seems to be the first reported case of limbic encephalitis associated with small cell carcinoma of the prostate. Implications with respect to diagnosis and therapy are discussed.
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14/820. Renal metastasis from prostatic adenocarcinoma: a potential diagnostic pitfall.

    We report a case of renal metastases from prostate cancer to show that the possibility of tumor metastasis, although rare, should always be considered in the differential diagnosis of renal mass.
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15/820. A case of adenocarcinoma with clear cell carcinoma of the bladder.

    A case of adenocarcinoma with clear cell carcinoma of the bladder in a 65-year-old male is reported. Our patient had a walnut-sized nodular tumor located on the anterior wall of the bladder. The patient underwent radical cystoprostatectomy with urethral hemi-Koch pouch. Histopathological examination revealed a lesion composed of poorly-differentiated adenocarcinoma and clear cell carcinoma with diffuse sheet patterns of cells with abundant, clear cytoplasm. The patient died of general metastasis 18 months after operation. To our knowledge this is the first case of adenocarcinoma with clear cell carcinoma arising from the anterior wall of the bladder in a male.
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16/820. disseminated intravascular coagulation in a patient treated with strontium-89 for metastatic carcinoma of the prostate.

    strontium-89 is effective in the palliation of bone pain caused by skeletal metastases. Its primary side effect is mild thrombocytopenia that typically recovers in 3 or 4 months. Subclinical disseminated intravascular coagulation is reported to be present in approximately 10% to 20% of patients with advanced prostate cancer. These patients may be at increased risk for severe marrow depression after radionuclide therapy for bone pain palliation. This report describes a patient with painful bony metastases resulting from prostate carcinoma. He had a normal platelet count and no clinical evidence of a coagulation disorder at the time of strontium-89 therapy, and a severe disseminated intravascular coagulation developed and lead to death after treatment. A normal platelet count before strontium-89 therapy does not preclude subsequent disseminated intravascular coagulation, and we support the Society of nuclear medicine's bone pain treatment procedure guideline that patients referred for bone palliation should be screened for disseminated intravascular coagulation before therapy.
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17/820. Sub-super bone scan caused by bone marrow involvement of prostate cancer.

    A 67-year-old man presented with malaise and marked anemia. A diagnostic workup revealed severe pancytopenia on a complete blood count and diffuse sclerotic change in the axial skeleton on a plain abdominal radiograph. Bone metastases being suspected from these findings, bone scintigraphy was performed. The bone scan demonstrated uniformly increased skeletal activity with faint soft-tissue activity. The findings of the bone scan, however, appeared atypical of the super scan caused by diffuse bone metastases, without any decrease in radioactivities of the appendicular skeleton and kidneys. bone marrow scintigraphy with In-111 chloride demonstrated central marrow failure and peripheral expansion, which indicated the possibility of myelophthisis. The patient underwent bone marrow biopsy, which revealed replacement of the bone marrow by metastatic adenocarcinoma. Further examinations detected the primary lesion in the prostate. In this case, the findings of the bone scan were insufficient for the super scan, and might be categorized as a sub-super scan. It would be important to recognize this incomplete form of super scan as a rare scintigraphic pattern of diffuse bone marrow metastases.
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18/820. Superior vena cava obstruction in prostate cancer.

    This report describes the case history of a man with adenocarcinoma of the prostate. After an initial response to maximal androgen blockade, he developed massive mediastinal and cervical lymphadenopathy, causing left recurrent laryngeal nerve palsy and superior vena cava obstruction. biopsy confirmed metastatic prostate cancer and he responded well to local radiotherapy. The hormonal treatment of advanced prostate cancer is discussed.
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19/820. Cushing's syndrome in prostate cancer. An aggressive course of prostatic malignancy.

    We report a case with an initial diagnosis of adenocarcinoma of the prostate in whom Cushing's syndrome developed. The disease did not respond to estrogen treatment and the patient died of severe septicemia. Histopathologic examination of the autopsy specimens revealed a small cell carcinoma intermingled with a moderately differentiated adenocarcinoma in the prostate and widespread metastases of small cell carcinoma. Immunoreactivity for neuroendocrine differentiation was found only in the small cell carcinoma. Determination of different tumor markers in plasma samples showed markedly elevated levels of prostate-specific antigen as well as carcinoembryonic antigen prior to treatment, with no significant changes after treatment. The concentration of the neuroendocrine marker chromogranin a was initially within the normal range, but increased during estrogen treatment, whilst neuron-specific enolase was moderately elevated throughout the observation period. copyright copyright 1999 S. Karger AG, Basel
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20/820. Loss of tissue immunoreactive androgen receptor in prostate cancer presenting initially as an intracranial tumor.

    We report a case of prostate cancer that presented initially as an intracranial tumor. biopsy specimens of the prostate before endocrine treatment were nearly negative immunohistochemically for prostate-specific antigen and the androgen receptors. All metastases including those in the brain expressed neither androgen receptor nor prostate-specific antigen at the protein and mRNA levels. The tumor, which did not respond to the anti-androgen therapy, had an aggressive course. In this case, the androgen-independent growth and rapid progression might be associated with the initial loss of the antigen and androgen characteristics of the prostate. copyright copyright 1999 S. Karger AG, Basel
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