1/4. Pulmonary sequestration with high levels of tumor markers tending to be misdiagnosed as lung cancer.A 62-year-old man with hemoptysis and an abnormal shadow on chest roentgenogram was diagnosed as having anomalous systemic arterial supply to the normal basal segment of the left lower lobe. The preoperative serum carbohydrate antigen 19-9 and carcinoembryonic antigen levels were 73.8 units/ml and 10.8 ng/ml, respectively. Histopathological examination confirmed that the lesion was an intralobar pulmonary sequestration without air connection. There was no malignant finding in the resected specimen. The serum values of tumor markers returned to their approximate normal ranges after lower lobectomy.- - - - - - - - - - ranking = 1keywords = antigen (Clic here for more details about this article) |
2/4. A case of intralobar pulmonary sequestration with calcification and elevated serum values of carcinoembryonic antigen and carbohydrate antigen 19-9.Pulmonary sequestration is uncommon. We report a case with radiographically visible calcification and elevated serum values of the tumor markers carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9.- - - - - - - - - - ranking = 5keywords = antigen (Clic here for more details about this article) |
3/4. CEA and CA 19-9 in benign pulmonary or mediastinal cystic lesions.serum carbohydrate antigen (CA) 19-9 was present at high levels in pulmonary sequestration, mediastinal bronchogenic cysts, and mediastinal mature teratomas. The fluid in the cysts of the lesions contained a high level of CA 19-9. After operation, the titer of serum CA 19-9 returned to normal ranges. Histological studies showed that mucosal epithelium stained positively for CA 19-9. We speculate that CA 19-9 concentrated in the cystic lesion might flow into the peripheral blood. carcinoembryonic antigen (CEA) was also present at high levels in the cyst fluid. CEA was positively stained in the epithelial cells using a polyclonal antibody but not a monoclonal antibody. The CEA detected at high concentration in the fluid was considered to be immunologically cross-reacting CEA.- - - - - - - - - - ranking = 1keywords = antigen (Clic here for more details about this article) |
4/4. A case of intralobar pulmonary sequestration with high serum CA19-9 levels.A 38-year-old female presented with cough and fever. A chest X-ray examination revealed an abnormal shadow in the posteroinferior portion of the left hemithorax, and a laboratory examination showed that the serum carbohydrate antigen 19-9 (CA19-9) level was markedly high (1000 U/ml). A left thoracotomy showed an intralobar pulmonary sequestration of the left lower lobe, and after a left lower lobe lobectomy, the serum level of CA19-9 decreased to normal. Increased CA19-9 activity was detected by immunohistochemistry in the epithelia of bronchioles in the pulmonary sequestration. This communication is the first to report a case of increased activity of CA19-9 in pulmonary sequestration.- - - - - - - - - - ranking = 0.5keywords = antigen (Clic here for more details about this article) |