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1/4. Abdominal tuberculosis in adolescents. Difficulties in diagnosis.

    Since the nature of abdominal tuberculosis is mimicking a number of diseases, this may cause delayed diagnosis resulting in evident increased morbidity and mortality. Most of the time, serologic and bacteriologic tools are not enough. We report 3 adolescents with distinct presentations, one mimicking Crohn's disease, one with hepatitis, and the last one with ascites. Terminal ileitis and mesenteric lymphadenitis were found in laparotomy of the first case mimicking crohn disease. Granulomatous hepatitis was found in the liver biopsy of the second patient, and peritonitis was found by laparoscopy of the third patient. tuberculosis could be diagnosed merely by histopathologic investigation. All were treated successfully without complication.
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ranking = 1
keywords = morbidity
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2/4. tuberculosis intestinal perforation during anti-tuberculosis treatment.

    intestinal perforation is an uncommon but potentially fatal complication of intestinal tuberculosis. We report on a 63-year-old hiv-negative man who developed terminal ileal perforation approximately 3.5 months following initiation of anti-tuberculous treatment for pulmonary tuberculosis and a concomitant tuberculous perianal abscess. Clinical and radiological improvements were initially evident following commencement of anti-tuberculous treatment, and the paradoxical response phenomenon was suspected. The patient subsequently underwent surgical resection of the affected bowel segment with primary anastomosis, and made an uneventful recovery. Anti-tuberculous medication was continued for another 12 months, and after a further 12 months there was no evidence of recurrent tuberculosis. This case illustrates that tuberculous intestinal perforation can develop during chemotherapy for tuberculosis. Prompt diagnosis and appropriate surgical treatment are essential to avoid morbidity and mortality.
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ranking = 1
keywords = morbidity
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3/4. Gastrointestinal tuberculosis: a retrospective review of 109 cases in a district general hospital.

    In a retrospective survey of 109 patients with gastrointestinal tuberculosis, 91 occurred in immigrants of Asian origin, six were diagnosed at post-mortem, and only 31 had evidence of pulmonary disease. abdominal pain, weight loss, fever and vomiting were the most common symptoms. barium contrast studies showed abnormalities in 56 per cent of cases but these could not be distinguished from the changes caused by other chronic inflammatory bowel diseases. Drug treatment was used in all patients, combined with biopsy in 37 and resection in 36. Results of treatment were good with low morbidity and mortality, there were few long-term problems and no relapses have occurred.
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ranking = 1
keywords = morbidity
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4/4. Oesophageal tuberculosis mimicking secondary oesophageal involvement of mediastinal neoplasm.

    During the last decade the number of cases of abdominal tuberculosis diagnosed in Western countries has dramatically increased. There are many reasons, including the appearance of AIDS and the increased morbidity of people across the world due to the westward migration of many people coming from areas with a high incidence of tuberculosis. Oesophageal involvement is rare in tuberculosis, occurring mainly as an extension of the disease from the adjacent tuberculous lymph nodes. Fifty-eight cases of oesophageal tuberculosis have so far been reported. We describe a patient affected by oesophageal tuberculosis mimicking secondary oesophageal involvement of mediastinal malignancy.
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ranking = 1
keywords = morbidity
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